Structure of PDB 3hph Chain D

Receptor sequence
>3hphD (length=196) Species: 36374 (Visna/maedi virus EV1 KV1772) [Search protein sequence]
ENIPLAEEEHNKWHQDAVSLHLEFGIPRTAAEDIVQQCDVCIDHWQVDYT
HYEDKIILVWVETNSGLIYAERVKGETGQEFRVQTMKWYAMFAPKSLQSD
NGPAFVAESTQLLMKYLGIEHTTGIPWNPQSQALVERTHQTLKNTLEKLI
PMFNAFESALAGTLITLNIKRKGGLGTSPMDIFIFNKEQQRIQQQS
3D structure
PDB3hph Structural basis for functional tetramerization of lentiviral integrase
ChainD
Resolution2.64 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.4: ribonuclease H.
3.4.23.-
3.6.1.23: dUTP diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN D H12 H16 C40 H10 H14 C38
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0015074 DNA integration

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3hph, PDBe:3hph, PDBj:3hph
PDBsum3hph
PubMed19609359
UniProtP35956|POL_VILVK Gag-Pol polyprotein (Gene Name=pol)

[Back to BioLiP]