Structure of PDB 3goy Chain D

Receptor sequence
>3goyD (length=182) Species: 9606 (Homo sapiens) [Search protein sequence]
KQQNFCVVELLPSDPEYNTVASKFNQTCSHFRIEKIERIQNPDLWNSYQA
KKKTMDAKNGQTMNEKQLFHGTDAGSVPHVNRNGFNRVAYGKGTYFAVNA
NYSANDTYSRPDANGRKHVYYVRVLTGIYTHGNHSLIVPPSKNPQNPTDL
YDTVTDNVHHPSLFVAFYDYQAYPEYLITFRK
3D structure
PDB3goy Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors.
ChainD
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3AB D H1601 Y1633 A1635 H70 Y95 A97
Gene Ontology
Molecular Function
GO:0003950 NAD+-protein poly-ADP-ribosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:3goy, PDBe:3goy, PDBj:3goy
PDBsum3goy
PubMed22343925
UniProtQ460N5|PAR14_HUMAN Protein mono-ADP-ribosyltransferase PARP14 (Gene Name=PARP14)

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