Structure of PDB 3gh8 Chain D

Receptor sequence
>3gh8D (length=220) Species: 10090 (Mus musculus) [Search protein sequence]
VEHIPFSHTRYPEQEMRMRSQEFYELLNKRRSVRFISSEHVPMEVIENVI
KAAGTAPSGAHTEPWTFVVVKDPDMKHKIREIIEEEEEINYMKRMGKRWV
TDLKKLRTNWIKEYLDTAPVLILIFKQVHGFAANGKKKVHYYNEISVSIA
CGLLLAALQNAGLVTVTTTPLNCGPRLRVLLGRPSHEKLLVLLPVGYPSR
DATVPDLKRKALDQIMVTVH
3D structure
PDB3gh8 Crystal structure of iodotyrosine deiodinase, a novel flavoprotein responsible for iodide salvage in thyroid glands.
ChainD
Resolution2.61 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.21.1.1: iodotyrosine deiodinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FMN D P123 S124 G125 H127 P57 S58 G59 H61
BS02 TYI D G125 A126 Y208 G59 A60 Y142
BS03 FMN D R96 R97 S98 R100 V232 T233 T234 T235 R30 R31 S32 R34 V166 T167 T168 T169
BS04 TYI D R100 E153 Y157 L169 L172 T174 K178 R34 E87 Y91 L103 L106 T108 K112
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity

View graph for
Molecular Function
External links
PDB RCSB:3gh8, PDBe:3gh8, PDBj:3gh8
PDBsum3gh8
PubMed19436071
UniProtQ9DCX8|IYD1_MOUSE Iodotyrosine deiodinase 1 (Gene Name=Iyd)

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