Structure of PDB 3gd3 Chain D

Receptor sequence
>3gd3D (length=465) Species: 10090 (Mus musculus) [Search protein sequence]
PSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKE
LWFSDDPNVTKTLQFRQWNGKERSIYFQPPSFYVSAQDLPNIENGGVAVL
TGKKVVHLDVRGNMVKLNDGSQITFEKCLIATGGTPRSLSAIDRAGAEVK
SRTTLFRKIGDFRALEKISREVKSITVIGGGFLGSELACALGRKSQASGI
EVIQLFPEKGNMGKILPQYLSNWTMEKVKREGVKVMPNAIVQSVGVSGGR
LLIKLKDGRKVETDHIVTAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQ
ARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWH
QSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQSGTGI
RSESETESEASEDYGKGVIFYLRDKVVVGIVLWNVFNRMPIARKIIKDGE
QHEDLNEVAKLFNIH
3D structure
PDB3gd3 Redox-linked conformational dynamics in apoptosis-inducing factor
ChainD
Resolution2.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.6.99.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FAD D G137 G138 G139 T140 A141 V161 S162 E163 R171 P172 S175 K176 K231 V232 T259 R284 G436 D437 H453 H454 A457 W482 G10 G11 G12 T13 A14 V34 S35 E36 R44 P45 S48 K49 K104 V105 T132 R157 G309 D310 H326 H327 A330 W355
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0046983 protein dimerization activity

View graph for
Molecular Function
External links
PDB RCSB:3gd3, PDBe:3gd3, PDBj:3gd3
PDBsum3gd3
PubMed19447115
UniProtQ9Z0X1|AIFM1_MOUSE Apoptosis-inducing factor 1, mitochondrial (Gene Name=Aifm1)

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