Structure of PDB 3gba Chain D

Receptor sequence
>3gbaD (length=250) Species: 10116 (Rattus norvegicus) [Search protein sequence]
TLIVTTILEEPYVMYRKSDPLYGNDRFEGYCLDLLKELSNILGFLYDVKL
VPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPF
MTLGISILYRKGTPIDSADDLAKQKIEYGAVRDGSTMTFFKKSKISTYEK
MWAFMSSRQSALVKNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQI
GGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCP
3D structure
PDB3gba Full Domain Closure of the Ligand-binding Core of the Ionotropic Glutamate Receptor iGluR5 Induced by the High Affinity Agonist Dysiherbaine and the Functional Antagonist 8,9-Dideoxyneodysiherbaine
ChainD
Resolution1.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DYH D E13 Y61 P88 L89 T90 R95 V137 G140 S141 T142 S173 M189 E190 S193 E9 Y56 P83 L84 T85 R90 V131 G134 S135 T136 S166 M182 E183 S186 MOAD: Ki=0.848nM
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:3gba, PDBe:3gba, PDBj:3gba
PDBsum3gba
PubMed19297335
UniProtP22756|GRIK1_RAT Glutamate receptor ionotropic, kainate 1 (Gene Name=Grik1)

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