Structure of PDB 3fyp Chain D

Receptor sequence
>3fypD (length=255) Species: 491 (Neisseria meningitidis serogroup B) [Search protein sequence]
MDIKINDITLGNNSPFVLFGGICVLESLDSTLQTCAHYVEVTRKLGIPYI
FKASFDKANRSSIYRGVGLEEGLKIFEKVKAEFGIPVITDVHEPHQCQPV
AEVCDVIQLPAFLARQTDLVVAMAKTGNVVNIKKPQFLSPSQMKNIVEKF
HEAGNGKLILCERGSSFGYDNLVVDMLGFGVMKQTCGNLPVIFDVTHSLQ
TGRRAQALDLALAGMATRLAGLFLESHPALPLHLLEDFLIRIKALDDLIK
SQPIL
3D structure
PDB3fyp Reversing evolution: re-establishing obligate metal ion dependence in a metal-independent KDO8P synthase
ChainD
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.55: 3-deoxy-8-phosphooctulonate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PEP D K52 A113 K135 R165 H199 K52 A111 K133 R163 H197
BS02 MN D C23 H199 E236 C23 H197 E225
Gene Ontology
Molecular Function
GO:0008676 3-deoxy-8-phosphooctulonate synthase activity
GO:0016740 transferase activity
Biological Process
GO:0009058 biosynthetic process
GO:0009103 lipopolysaccharide biosynthetic process
GO:0019294 keto-3-deoxy-D-manno-octulosonic acid biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:3fyp, PDBe:3fyp, PDBj:3fyp
PDBsum3fyp
PubMed19447118
UniProtQ9JZ55|KDSA_NEIMB 2-dehydro-3-deoxyphosphooctonate aldolase (Gene Name=kdsA)

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