Structure of PDB 3f7g Chain D

Receptor sequence
>3f7gD (length=100) Species: 9606 (Homo sapiens) [Search protein sequence]
AGATLSRGPAFPGMGSEELRLASFYDWPLTAEVPPELLAAAGFFHTGHQD
KVRCFFCYGGLQSWKRGDDPWTEHAKWFPSCQFLLRSKGRDFVHSVQETH
3D structure
PDB3f7g Orally bioavailable antagonists of inhibitor of apoptosis proteins based on an azabicyclooctane scaffold
ChainD
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) F81
Catalytic site (residue number reindexed from 1) F11
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN D C124 C127 H144 C151 C54 C57 H74 C81
External links
PDB RCSB:3f7g, PDBe:3f7g, PDBj:3f7g
PDBsum3f7g
PubMed19228017
UniProtQ96CA5|BIRC7_HUMAN Baculoviral IAP repeat-containing protein 7 (Gene Name=BIRC7)

[Back to BioLiP]