Structure of PDB 3f27 Chain D

Receptor sequence
>3f27D (length=74) Species: 10090 (Mus musculus) [Search protein sequence]
IRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPF
VEEAERLRVQHMQDHPNYKYRPRR
3D structure
PDB3f27 The Structure of Sox17 Bound to DNA Reveals a Conserved Bending Topology but Selective Protein Interaction Platforms
ChainD
Resolution2.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D R70 N73 F75 S99 W106 Y137 R141 R3 N6 F8 S32 W39 Y70 R74 PDBbind-CN: Kd=2.6nM
BS02 dna D R69 R70 M72 M76 K80 R83 H94 N95 Y137 R2 R3 M5 M9 K13 R16 H27 N28 Y70 PDBbind-CN: Kd=2.6nM
External links
PDB RCSB:3f27, PDBe:3f27, PDBj:3f27
PDBsum3f27
PubMed19328208
UniProtQ61473|SOX17_MOUSE Transcription factor SOX-17 (Gene Name=Sox17)

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