Structure of PDB 3ej6 Chain D

Receptor sequence
>3ej6D (length=681) Species: 5141 (Neurospora crassa) [Search protein sequence]
EVDARQRLKEVEVDDNGQFMTTDFGGNIEEQFSLKAGGRGSTLLEDFIFR
QKLQHFDHERIPERVVHARGAGAHGIFTSYGDWSNITAASFLGAKDKQTP
VFVRFSTVAGSRGSADTARDVHGFATRFYTDEGNFDIVGNNIPVFFIQDA
IRFPDLIHSVKPSPDNEVPQAATAHDSAWDFFSSQPSALHTLFWAMSGNG
IPRSYRHMDGFGIHTFRLVTEDGKSKLVKWHWKTKQGKAALVWEEAQVLA
GKNADFHRQDLWDAIESGNAPSWELAVQLIDEDKAQAYGFDLLDPTKFLP
EEFAPLQVLGEMTLNRNPMNYFAETEQISFQPGHIVRGVDFTEDPLLQGR
LYSYLDTQLNRHRGPNFEQLPINRPVSGVHNNHRDGQGQAWIHKNIHHYS
PSYLNKGYPAQANQTVGRGFFTTPGRTASGVLNRELSATFDDHYTQPRLF
FNSLTPVEQQFVINAIRFEASHVTNEQVKKNVLEQLNKISNDVAKRVAVA
LGLEAPQPDPTYYHNNVTRGVSIFNESLPTIATLRVGVLSTTKGGSLDKA
KALKEQLEKDGLKVTVIAEYLASGVDQTYSAADATAFDAVVVAEGAERVF
SGKGAMSPLFPAGRPSQILTDGYRWGKPVAAVGSAKKALQSIGVEEKEAG
VYAGAQDEVIKGVEEGLKVFKFLERFAVDGD
3D structure
PDB3ej6 Structure-Function Relationships in Fungal Large-Subunit Catalases
ChainD
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H102 N175 Q366
Catalytic site (residue number reindexed from 1) H67 N140 Q331
Enzyme Commision number 1.11.1.6: catalase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM D R99 V101 H102 R139 V173 G174 N175 F180 F188 I248 H249 F365 L381 G384 R385 S388 Y389 T392 Q393 R396 R64 V66 H67 R104 V138 G139 N140 F145 F153 I213 H214 F330 L346 G349 R350 S353 Y354 T357 Q358 R361
Gene Ontology
Molecular Function
GO:0004096 catalase activity
GO:0004601 peroxidase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0006979 response to oxidative stress
GO:0042744 hydrogen peroxide catabolic process
GO:0098869 cellular oxidant detoxification
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3ej6, PDBe:3ej6, PDBj:3ej6
PDBsum3ej6
PubMed19109972
UniProtQ9C169|CAT3_NEUCR Catalase-3 (Gene Name=cat-3)

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