Structure of PDB 3edr Chain D

Receptor sequence
>3edrD (length=93) Species: 9606 (Homo sapiens) [Search protein sequence]
YKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQ
ILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
3D structure
PDB3edr Structural basis for executioner caspase recognition of P5 position in substrates.
ChainD
Resolution2.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.60: caspase-7.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide D Y530 S531 W532 R533 S534 P535 Q576 D578 Y20 S21 W22 R23 S24 P25 Q66 D68
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function

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Biological Process
External links
PDB RCSB:3edr, PDBe:3edr, PDBj:3edr
PDBsum3edr
PubMed18780184
UniProtP55210|CASP7_HUMAN Caspase-7 (Gene Name=CASP7)

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