Structure of PDB 3e3i Chain D

Receptor sequence
>3e3iD (length=213) Species: 727 (Haemophilus influenzae) [Search protein sequence]
MDKIKQLFANNYSWAQRMKEELADHQTPHYLWIACSDSRVPAEKLTNLEP
GELFVHRNVANQVIHTDFNCLSVVQYAVDVLKIEHIIICGHTNCGGIHAA
MADKDLGLINNWLLHIRDIWFKHGHLLGKLSPEKRADMLTKINVAEQVYN
LGRTSIVKSAWERGQKLSLHGWVYDVNDGFLVDQGVMATSRETLEISYRN
AIARLSILDEENI
3D structure
PDB3e3i Evidence for a bicarbonate "escort" site in Haemophilus influenzae beta-carbonic anhydrase .
ChainD
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) C42 D44 R46 H98 C101
Catalytic site (residue number reindexed from 1) C35 D37 R39 H91 C94
Enzyme Commision number 4.2.1.1: carbonic anhydrase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SO4 D R160 R198 R153 R191
BS02 ZN D C42 D44 H98 C101 C35 D37 H91 C94
BS03 BCT D V47 P48 R64 Y181 V40 P41 R57 Y174
Gene Ontology
Molecular Function
GO:0004089 carbonate dehydratase activity
GO:0008270 zinc ion binding
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0015976 carbon utilization
Cellular Component
GO:0005575 cellular_component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3e3i, PDBe:3e3i, PDBj:3e3i
PDBsum3e3i
PubMed20359198
UniProtP45148|CAN_HAEIN Carbonic anhydrase 2 (Gene Name=can)

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