Structure of PDB 3dr7 Chain D

Receptor sequence
>3dr7D (length=367) Species: 190650 (Caulobacter vibrioides CB15) [Search protein sequence]
PRISVAAPRLDGNERDYVLECMDTTWISSVGRFIVEFEKAFADYCGVKHA
IACNNGTTALHLALVAMGIGPGDEVIVPSLTYIASANSVTYCGATPVLVD
NDPRTFNLDAAKLEALITPRTKAIMPVHLYGQICDMDPILEVARRHNLLV
IEDAAEAVGATYRGKKSGSLGDCATFSFFGNKIITTGEGGMITTNDDDLA
AKMRLLRGQGMDPNRRYWFPIVGFNYRMTNIQAAIGLAQLERVDEHLAAR
ERVVGWYEQKLARLGNRVTKPHVALTGRHVFWMYTVRLGEGLSTTRDQVI
KDLDALGIESRPVFHPMHIMPPYAHLATDDLKIAEACGVDGLNLPTHAGL
TEADIDRVIAALDQVLV
3D structure
PDB3dr7 Accommodation of GDP-linked sugars in the active site of GDP-perosamine synthase
ChainD
Resolution1.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y86 D157 E160 F183 K186 Y221 R231
Catalytic site (residue number reindexed from 1) Y82 D153 E156 F179 K182 Y217 R227
Enzyme Commision number 2.6.1.102: GDP-perosamine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GPD D T29 W30 S32 R220 Y221 T25 W26 S28 R216 Y217
BS02 GPD D A10 P12 Y86 F183 G184 N185 X186 E313 F318 A6 P8 Y82 F179 G180 N181 X182 E309 F314
Gene Ontology
Molecular Function
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding
GO:0102933 GDP-4-dehydro-6-deoxy-D-mannose-4-aminotransferase activity
Biological Process
GO:0000271 polysaccharide biosynthetic process
GO:0009103 lipopolysaccharide biosynthetic process
GO:0009243 O antigen biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3dr7, PDBe:3dr7, PDBj:3dr7
PDBsum3dr7
PubMed18795799
UniProtQ9A9H3|GDPPS_CAUVC GDP-perosamine synthase (Gene Name=per)

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