Structure of PDB 3b03 Chain D

Receptor sequence
>3b03D (length=364) Species: 2286 (Saccharolobus shibatae) [Search protein sequence]
IVNRKVEHVEIAAFENVDGLSSSTFLNDVILVHQGFPGISFSEINTKTKF
FRKEISVPVMVTGMTGGRNELGRINKIIAEVAEKFGIPMGVGSQRVAIEK
AEARESFAIVRKVAPTIPIIANLGMPQLVKGYGLKEFQDAIQMIEADAIA
VHLNPAQEVFQPEGEPEYQIYALEKLRDISKELSVPIIVKESGNGISMET
AKLLYSYGIKNFDTSGQGGTNWIAIEMIRDIRRGNWKAESAKNFLDWGVP
TAASIMEVRYSVPDSFLVGSGGIRSGLDAAKAIALGADIAGMALPVLKSA
IEGKESLEQFFRKIIFELKAAMMLTGSKDVDALKKTSIVILGKLKEWAEY
RGINLSIYEKVRKR
3D structure
PDB3b03 Covalent modification of reduced flavin mononucleotide in type-2 isopentenyl diphosphate isomerase by active-site-directed inhibitors.
ChainD
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.3.3.2: isopentenyl-diphosphate Delta-isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 VNR D R7 K8 T65 G66 M67 G95 S96 R98 N125 H155 N157 Q160 K193 S195 S218 G222 T223 W225 R277 A296 L297 R4 K5 T62 G63 M64 G92 S93 R95 N122 H152 N154 Q157 K190 S192 S215 G219 T220 W222 R274 A293 L294
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004452 isopentenyl-diphosphate delta-isomerase activity
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity
GO:0016853 isomerase activity
GO:0046872 metal ion binding
GO:0070402 NADPH binding
Biological Process
GO:0008299 isoprenoid biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3b03, PDBe:3b03, PDBj:3b03
PDBsum3b03
PubMed22158896
UniProtP61615|IDI2_SACSH Isopentenyl-diphosphate delta-isomerase (Gene Name=fni)

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