Structure of PDB 3a9c Chain D

Receptor sequence
>3a9cD (length=322) Species: 311400 (Thermococcus kodakarensis) [Search protein sequence]
MAVVKEVLEIAEKIKNMEIRGAGKIARSAAYALQLQAEKSKATNVDEFWK
EMKQAAKILFETRPTAVSLPNALRYVMHRGKIAYSSGADLEQLRFVIINA
AKEFIHNSEKALERIGEFGAKRIEDGDVIMTHCHSKAAISVMKTAWEQGK
DIKVIVTETRPKWQGKITAKELASYGIPVIYVVDSAARHYMKMTDKVVMG
ADSITVNGAVINKIGTALIALTAKEHRVWTMIAAETYKFHPETMLGQLVE
IEMRDPTEVIPEDELKTWPKNIEVWNPAFDVTPPEYVDVIITERGIIPPY
AAIDILREEFGWALKYTEPWED
3D structure
PDB3a9c Dynamic, ligand-dependent conformational change triggers reaction of ribose-1,5-bisphosphate isomerase from Thermococcus kodakarensis KOD1
ChainD
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.3.1.29: ribose-1,5-bisphosphate isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 RUB D A133 S135 K136 A137 A201 N212 K213 K238 R254 A133 S135 K136 A137 A201 N212 K213 K238 R254
Gene Ontology
Molecular Function
GO:0016853 isomerase activity
GO:0043917 ribose 1,5-bisphosphate isomerase activity
GO:0046523 S-methyl-5-thioribose-1-phosphate isomerase activity
Biological Process
GO:0019323 pentose catabolic process
GO:0019509 L-methionine salvage from methylthioadenosine
GO:0044237 cellular metabolic process
GO:0044249 cellular biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3a9c, PDBe:3a9c, PDBj:3a9c
PDBsum3a9c
PubMed22511789
UniProtQ5JFM9|R15PI_THEKO Ribose 1,5-bisphosphate isomerase (Gene Name=TK0185)

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