Structure of PDB 2y3r Chain D

Receptor sequence

>2y3rD (length=491) Species: 529089 (Streptomyces sp. 307-9) [Search protein sequence]

DSVAPGDIRYEDLRRGENLRFVGDPEEIHLVGSAAEIEQVLSRAVRSGKR
VAVRSGGHCYEDFVANSDVRVVMDMSRLSAVGFDEERGAFAVEAGATLGA
VYKTLFRVWGVTLPGGACPDVGAGGHILGGGYGPLSRMHGSIVDYLHAVE
VVVVDASGDARTVIATREPSDPNHDLWWAHTGGGGGNFGVVVRYWLRTAP
PEPGRLLPRPPAEVLLNTTVWPWEGLDEAAFARLVRNHGRWFEQNSGPDS
PWCDLYSVLALTRSQSGALAMTTQLDATGPDAEKRLETYLAAVSEGVGVQ
PHSDTRRLPWLHSTRWPGIAGDGDMTGRAKIKAAYARRSFDDRQIGTLYT
RLTSTYDNPAGVVALIAYGGKVNAVPADRTAVAQRDSILKIVYVTTWEDP
AQDPVHVRWIRELYRDVYADTGGVPVPGGAADGAYVNYPDVDLADEEWNT
SGVPWSELYYKDAYPRLQAVKARWDPRNVFRHALSVRVPPA

3D structure

PDB

2y3r Tirandamycin Biosynthesis is Mediated by Co-Dependent Oxidative Enzymes

Chain

Resolution

1.79 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	D	V57 R58 S59 G60 G61 H62 C63 Y64 F67 V68 G120 A121 C122 V125 G126 G129 H130 Y136 G189 G190 V195 Y444 N446	V53 R54 S55 G56 G57 H58 C59 Y60 F63 V64 G116 A117 C118 V121 G122 G125 H126 Y132 G185 G186 V191 Y435 N437
BS02	TRK	D	Y64 D332 A337 I339 T405 Y447	Y60 D324 A329 I331 T396 Y438

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0016491	oxidoreductase activity
GO:0046872	metal ion binding
GO:0050660	flavin adenine dinucleotide binding
GO:0071949	FAD binding

View graph for
Molecular Function

External links

PDB	RCSB:2y3r, PDBe:2y3r, PDBj:2y3r
PDBsum	2y3r
PubMed	21778983
UniProt	D3Y1I2

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