Structure of PDB 2x4m Chain D

Receptor sequence
>2x4mD (length=293) Species: 632 (Yersinia pestis) [Search protein sequence]
SSQLIPNISPDSFTVAASTGMLSGKSHEMLYDAETGRKISQLDWKIKNVA
ILKGDISWDPYSFLTLNARGWTSLASGSGNMDDYAWMNENQSEWTDHSSH
PATNVNHANEYDLNVKGWLLQDENYKAGITAGYQETRFSWTATGGSYSYN
NGAYTGNFPKGVRVIGYNQRFSMPYIGLAGQYRINDFELNALFKFSDWVR
AHDNDEHYMRDLTFREKTSGSRYYGTVINAGYYVTPNAKVFAEFTYSKYD
EGKGGTQTIDKNSGDSVSIGGDAAGISNKNYTVTAGLQYRFGG
3D structure
PDB2x4m An Active Site Water Network in the Plasminogen Activator Pla from Yersinia Pestis
ChainD
Resolution2.55 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D84 A86 S99 D206 H208
Catalytic site (residue number reindexed from 1) D83 A85 S98 D205 H207
Enzyme Commision number 3.4.23.48: plasminogen activator Pla.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 C8E D K54 G55 W72 E111 K53 G54 W71 E110
BS02 C8E D G55 A69 R70 Y112 G54 A68 R69 Y111
BS03 C8E D H208 R211 H207 R210
Gene Ontology
Molecular Function
GO:0004175 endopeptidase activity
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0009279 cell outer membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2x4m, PDBe:2x4m, PDBj:2x4m
PDBsum2x4m
PubMed20637417
UniProtP17811|PLA_YERPE Plasminogen activator (Gene Name=pla)

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