Structure of PDB 2wrf Chain D

Receptor sequence
>2wrfD (length=486) Species: 139280 (Influenza A virus (A/chicken/Potsdam/4705/1984(H2N2))) [Search protein sequence]
ICVGYHSNNSTEKVDTILERNVTVTHAQDILEKTHNGKLCKLNGIPPLEL
GDCSIAGWLLGNPECDRLLTVPEWSYIMEKENPRNGLCYPGSFNDYEELK
HLISSVTHFEKVKILPKDRWTQHTTTGGSQGCAVFDNPSFFRNMVWLTKK
GSNYPVAKGSYNNTSGEQMLIIWGVHHPNDETEQRTLYQNVGAYVSVGTS
TLNKRSLPEIATRPEVNGQGGRMEFSWTILDIWDTINFESTGNLIAPEYG
FKISKRGSSGIMKTEGTLENCETKCQTPLGAINTTLPFHNIHPLTIGECP
KYVKSERLVLATGLRNVPQGLFGAIAGFIEGGWQGMVDGWYGYHHSNDQG
SGYAADKESTQKAFDGITNKVNSVIEKMNTQFEAVGKEFSNLEKRLENLN
KKMEDGFLDVWTYNAELLVLMENEMTLDFHDSNVKNLYDKVRMQLRDNVK
ELGNGCFEFYHKCDDECMNSVKNGTYDYSKYEEESK
3D structure
PDB2wrf From the Cover: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957.
ChainD
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SIA D Y95 G134 S135 W152 H182 E189 L193 Q225 Y89 G128 S129 W146 H176 E183 L187 Q219
Gene Ontology
Molecular Function
GO:0046789 host cell surface receptor binding
Biological Process
GO:0019062 virion attachment to host cell
GO:0019064 fusion of virus membrane with host plasma membrane
GO:0039654 fusion of virus membrane with host endosome membrane
GO:0046718 symbiont entry into host cell
GO:0046761 viral budding from plasma membrane
GO:0075512 clathrin-dependent endocytosis of virus by host cell
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016324 apical plasma membrane
GO:0019031 viral envelope
GO:0020002 host cell plasma membrane
GO:0055036 virion membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2wrf, PDBe:2wrf, PDBj:2wrf
PDBsum2wrf
PubMed19805083
UniProtQ67326

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