Structure of PDB 2wfy Chain D

Receptor sequence
>2wfyD (length=260) Species: 9606 (Homo sapiens) [Search protein sequence]
NEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVG
EEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYP
PEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQ
QPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSW
PESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVS
LLNPPETLNL
3D structure
PDB2wfy Truncation and Optimisation of Peptide Inhibitors of Cyclin-Dependent Kinase 2-Cyclin a Through Structure-Guided Design.
ChainD
Resolution2.53 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D M210 I213 E220 Q254 I281 T282 T285 M38 I41 E48 Q82 I109 T110 T113
Gene Ontology
Molecular Function
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
Biological Process
GO:0044772 mitotic cell cycle phase transition

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Molecular Function
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Biological Process
External links
PDB RCSB:2wfy, PDBe:2wfy, PDBj:2wfy
PDBsum2wfy
PubMed19472269
UniProtP20248|CCNA2_HUMAN Cyclin-A2 (Gene Name=CCNA2)

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