Structure of PDB 2vrt Chain D

Receptor sequence
>2vrtD (length=487) Species: 562 (Escherichia coli) [Search protein sequence]
MKRMLINATQQEELRVALVDGQRLYDLDIESPEQKKANIYKGKITRIEPS
LEAAFVDYGAERHGFLPLKEIAREYFPRPNIKDVLREGQEVIVQIDKEER
GNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIEDDRTELKEALASLEL
PEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFLIHQE
SNVIVRAFRDYLRQDIGEILIDNPKVLELARQHIAALGRPDFSSKIKLYT
GEIPLFSHYQIESQIESAFQREVRLPSGGSIVIDSTEALTAIDINSARDI
EETAFNTNLEAADEIARQLRLRDLGGLIVIDFIDMTPVRHQRAVENRLRE
AVRQDRARIQISHISRFGLLEMSRQRLSSHHVCPRCSGTGTVRDNESLSL
SILRLIEEEALKENTQEVHAIVPVPIASYLLNEKRSAVNAIETRQDGVRC
VIVPNDQMETPHYHVLRVRKGEETPTLSYMLPKLHEE
3D structure
PDB2vrt The Crystal Structure of the Escherichia Coli Rnase E Apoprotein and a Mechanism for RNA Degradation.
ChainD
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.26.12: ribonuclease E.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna D G137 I139 S140 R141 R169 T170 G128 I130 S131 R132 R159 T160
BS02 ZN D C404 C407 C383 C386
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004540 RNA nuclease activity
GO:0008995 ribonuclease E activity
Biological Process
GO:0006396 RNA processing

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Molecular Function
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Biological Process
External links
PDB RCSB:2vrt, PDBe:2vrt, PDBj:2vrt
PDBsum2vrt
PubMed18682225
UniProtP21513|RNE_ECOLI Ribonuclease E (Gene Name=rne)

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