Structure of PDB 2rex Chain D

Receptor sequence
>2rexD (length=180) Species: 9606 (Homo sapiens) [Search protein sequence]
PQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLET
EEQRVELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVALKKWR
TEILDYCPSTRVLLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQ
LGAEIYLEGSAFTSEKSIHSIFRTASMLCL
3D structure
PDB2rex Crystal structure of the effector domain of PLXNB1 bound with Rnd1 GTPase.
ChainD
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG D T27 T45 T21 T39
BS02 CA D Y38 E40 Y32 E34
BS03 GNP D V22 Q23 G25 K26 T27 A28 Y38 P39 E40 Y42 T45 K126 D128 L129 F170 V16 Q17 G19 K20 T21 A22 Y32 P33 E34 Y36 T39 K118 D120 L121 F162
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007264 small GTPase-mediated signal transduction

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Molecular Function
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Biological Process
External links
PDB RCSB:2rex, PDBe:2rex, PDBj:2rex
PDBsum2rex
PubMed
UniProtQ92730|RND1_HUMAN Rho-related GTP-binding protein Rho6 (Gene Name=RND1)

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