Structure of PDB 2r35 Chain D

Receptor sequence
>2r35D (length=30) Species: 9606 (Homo sapiens) [Search protein sequence]
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
3D structure
PDB2r35 Metal induced structural changes observed in hexameric insulin
ChainD
Resolution2.08 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide D G8 V12 Y16 F24 F25 Y26 G8 V12 Y16 F24 F25 Y26
BS02 peptide D F1 N3 H5 C7 L15 V18 C19 R22 G23 F24 F25 Y26 T27 T30 F1 N3 H5 C7 L15 V18 C19 R22 G23 F24 F25 Y26 T27 T30
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:2r35, PDBe:2r35, PDBj:2r35
PDBsum2r35
PubMed18977386
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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