Structure of PDB 2qlj Chain D

Receptor sequence
>2qljD (length=93) Species: 9606 (Homo sapiens) [Search protein sequence]
YKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQ
ILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
3D structure
PDB2qlj Plasticity of S2-S4 specificity pockets of executioner caspase-7 revealed by structural and kinetic analysis.
ChainD
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.60: caspase-7.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D Y530 S531 W532 R533 S534 P535 R537 W540 S575 Q576 Y20 S21 W22 R23 S24 P25 R27 W30 S65 Q66
BS02 peptide D Q560 Y600 Q50 Y90
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:2qlj, PDBe:2qlj, PDBj:2qlj
PDBsum2qlj
PubMed17697120
UniProtP55210|CASP7_HUMAN Caspase-7 (Gene Name=CASP7)

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