Structure of PDB 2ql7 Chain D

Receptor sequence
>2ql7D (length=92) Species: 9606 (Homo sapiens) [Search protein sequence]
KIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQI
LTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYFSQ
3D structure
PDB2ql7 Plasticity of S2-S4 specificity pockets of executioner caspase-7 revealed by structural and kinetic analysis.
ChainD
Resolution2.4 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.4.22.60: caspase-7.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D Y530 S531 W532 R533 P535 W540 Y19 S20 W21 R22 P24 W29
BS02 peptide D Q560 Y600 Q49 Y89
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2ql7, PDBe:2ql7, PDBj:2ql7
PDBsum2ql7
PubMed17697120
UniProtP55210|CASP7_HUMAN Caspase-7 (Gene Name=CASP7)

[Back to BioLiP]