Structure of PDB 2qki Chain D

Receptor sequence
>2qkiD (length=632) Species: 9606 (Homo sapiens) [Search protein sequence]
SPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVHDFPGKKLVLSSE
KTVLTPATNHMGNVTFTIPSEKGRNKFVTVQATFGTQVVEKVVLVSLQSG
YLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQD
SLSSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYV
LPSFEVIVEPTEKFYYIYNEKGLEVTITARFLYGKKVEGTAFVIFGIQDG
EQRISLPESLKRIPIEDGSGEVVLSRKVLLDGVQNLRAEDLVGKSLYVSA
TVILHSGSDMVQAERSGIPIVTSPYQIHFTKTPKYFKPGMPFDLMVFVTN
PDGSPAYRVPVAVQGEDTVQSLTQGDGVAKLSINTHPSQKPLSITVRTKK
QELSEAEQATRTMQALPYSTVGNSNNYLHLSVLRTELRPGETLNVNFLLR
MDRAHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDFIPS
FRLVAYYTLIGASGQREVVADSVWVDVKDSCVGSLVVKSGQPVPGQQMTL
KIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKADIGCTPGSGK
DYAGVFSDAGLTFTSSSGQQTAQRAELQCPQP
3D structure
PDB2qki Structure of compstatin in complex with complement component C3c reveals a new mechanism of complement inhibition.
ChainD
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D G345 P347 N390 T391 L454 L455 R456 M457 R459 E462 R486 D491 L492 G339 P341 N384 T385 L448 L449 R450 M451 R453 E456 R480 D485 L486
Gene Ontology
Molecular Function
GO:0004866 endopeptidase inhibitor activity

View graph for
Molecular Function
External links
PDB RCSB:2qki, PDBe:2qki, PDBj:2qki
PDBsum2qki
PubMed17684013
UniProtP01024|CO3_HUMAN Complement C3 (Gene Name=C3)

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