Structure of PDB 2pzv Chain D

Receptor sequence
>2pzvD (length=123) Species: 303 (Pseudomonas putida) [Search protein sequence]
NLPTAQEVQGLMARYIELVDVGDIEAIVQMYADDATVENPFGQPPIHGRE
QIAAFYRQGLKVRACLTGPVRASHNGCGAMPFRVEMVWNGQPCALDVIDV
MRFDEHGRIQTMQAYWSEVNLSV
3D structure
PDB2pzv Testing Electrostatic complementarity in Enzyme Catalysis: Hydrogen Bonding in the Ketosteroid Isomerase Oxyanion Hole
ChainD
Resolution1.25 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y16 N40 D100 D103
Catalytic site (residue number reindexed from 1) Y15 N39 D96 D99
Enzyme Commision number 5.3.3.1: steroid Delta-isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IPH D Y16 N40 F86 V101 D103 Y15 N39 F82 V97 D99 MOAD: Kd=135uM
Gene Ontology
Molecular Function
GO:0004769 steroid delta-isomerase activity
GO:0016853 isomerase activity
Biological Process
GO:0008202 steroid metabolic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2pzv, PDBe:2pzv, PDBj:2pzv
PDBsum2pzv
PubMed16602823
UniProtP07445|SDIS_PSEPU Steroid Delta-isomerase (Gene Name=ksi)

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