Structure of PDB 2p5g Chain D

Receptor sequence
>2p5gD (length=875) Species: 12353 (Escherichia phage RB69) [Search protein sequence]
KEFYLTVEQIGDSIFERYIDSNGRERTREVEYKPSLFAHCPESQATKYFD
IYGKPCTRKLFANMRDASQWIKRMEDIGLEALGMDDFKLAYLSDTYNYEI
KYDHTKIRVANFDIEVTSPDGFPEPSQAKHPIDAITHYDSIDDRFYVFDL
LNSPYGNVEEWSIEIAAGGDEVPSEIIDKIIYMPFDNEKELLMEYLNFWQ
QKTPVILTGWNVESFAIPYVYNRIKNIFGESTAKRLSPHRKTRVKVIENM
YGSREIITLFGISVLDYIDLYKKFSFTNQPSYSLDYISEFELNVGKLKYD
GPISKLRESNHQRYISYNIIAVYRVLQIDAKRQFINLSLDMGYYAKIQIQ
SVFSPIKTWDAIIFNSLKEQNKVIPQGRSHPVQPYPGAFVKEPIPNRYKY
VMSFDLTSLYPSIIRQVNISPETIAGTFKVAPLHDYINAVAERPSDVYSC
SPNGMMYYKDRDGVVPTEITKVFNQRKEHKGYMLAAQRNGEIIKEAPLDV
DYRFDDEIKEKIKKLSAKSLNEMLFRAQRTEVAGMTAQINRKLLINSLYG
ALGNVWFRYYDLRNATAITTFGQMALQWIERKVNEYLNEVCGTEGEAFVL
YGDTDSIYVSADKIIDKVGESKFRDTNHWVDFLDKFARERMEPAIDRGFR
EMCEYMNNKQHLMFMDREAIAGPPLGSKGIGGFWTGKKRYALNVWDMEGT
RYAEPKLKIMGLETQKSSTPKAVQKALKECIRRMLQEGEESLQEYFKEFE
KEFRQLNYISIASVSSANNIAKYDVGGFPGPKCPFHIRGILTYNRAIPQV
VEGEKVYVLPLREGNPFGDKCIAWPSGTEITDLIKDDVLHWMDYTVLLEK
TFIKPLEGFTSAAKLDYEKKASLFD
3D structure
PDB2p5g Caught bending the a-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide.
ChainD
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
3.1.11.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D P799 K800 K874 P781 K782 K850
BS02 dna D Q733 S735 S783 S784 N786 H804 Q715 S717 S765 S766 N768 H786
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0004527 exonuclease activity
GO:0008408 3'-5' exonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0039686 bidirectional double-stranded viral DNA replication
GO:0039693 viral DNA genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:2p5g, PDBe:2p5g, PDBj:2p5g
PDBsum2p5g
PubMed17718515
UniProtQ38087|DPOL_BPR69 DNA-directed DNA polymerase (Gene Name=43)

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