Structure of PDB 2oby Chain D

Receptor sequence
>2obyD (length=334) Species: 9606 (Homo sapiens) [Search protein sequence]
IPMLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQ
GQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQY
VTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHA
GLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFS
EATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDING
PLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLL
PVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ
3D structure
PDB2oby Crystal structure of human P53 inducible oxidoreductase (TP53I3, PIG3)
ChainD
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.6.5.5: NADPH:quinone reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP D N40 R41 E123 T127 A148 S151 G152 V153 A172 G173 K177 Y192 Y238 M241 L265 L266 M317 N322 N42 R43 E125 T129 A150 S153 G154 V155 A174 G175 K179 Y194 Y240 M243 L267 L268 M319 N324
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0003960 NADPH:quinone reductase activity
GO:0016491 oxidoreductase activity
GO:0042803 protein homodimerization activity
GO:0048038 quinone binding
GO:0070402 NADPH binding
Biological Process
GO:0006739 NADP metabolic process
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:2oby, PDBe:2oby, PDBj:2oby
PDBsum2oby
PubMed
UniProtQ53FA7|QORX_HUMAN Quinone oxidoreductase PIG3 (Gene Name=TP53I3)

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