Structure of PDB 2mse Chain D

Receptor sequence
>2mseD (length=73) Species: 9606 (Homo sapiens) [Search protein sequence]
GTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCVVYRLIKGR
KTVTAWDTAIAPLDGEELIVEVL
3D structure
PDB2mse Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site.
ChainD
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 17F D K858 I876 K51 I69
BS02 17F D R857 K858 R50 K51
BS03 17F D K855 G856 K48 G49
Gene Ontology
Biological Process
GO:0007165 signal transduction

View graph for
Biological Process
External links
PDB RCSB:2mse, PDBe:2mse, PDBj:2mse
PDBsum2mse
PubMed25941399
UniProtP10398|ARAF_HUMAN Serine/threonine-protein kinase A-Raf (Gene Name=ARAF)

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