Structure of PDB 2jg8 Chain D

Receptor sequence
>2jg8D (length=133) Species: 9606 (Homo sapiens) [Search protein sequence]
QPRPAFSAIRRNPPMGGNVVIFDTVITNQEEPYQNHSGRFVCTVPGYYYF
TFQVLSQWEICLSIVSSSRGQVRRSLGFCDTTNKGLFQVVSGGMVLQLQQ
GDQVWVEKDPKKGHIYQGSEADSVFSGFLIFPS
3D structure
PDB2jg8 C1Q Binds Phosphatidylserine and Likely Acts as a Multiligand-Bridging Molecule in Apoptotic Cell Recognition.
ChainD
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SEP D Q160 R162 Q71 R73 MOAD: Kd=37nM
PDBbind-CN: -logKd/Ki=6.30,Kd=0.5uM
External links
PDB RCSB:2jg8, PDBe:2jg8, PDBj:2jg8
PDBsum2jg8
PubMed18250442
UniProtP02745|C1QA_HUMAN Complement C1q subcomponent subunit A (Gene Name=C1QA)

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