Structure of PDB 2isz Chain D

Receptor sequence
>2iszD (length=140) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
MNELVDTTEMYLRTIYDLEEEGVTPLRARIAERLDQSGPTVSQTVSRMER
DGLLRVAGDRHLELTEKGRALAIAVMRKHRLAERLLVDVIGLPWEEVHAE
ACRWEHVMSEDVERRLVKVLNNPTTSPFGNPIPGLVELGV
3D structure
PDB2isz Crystal structures, metal activation, and DNA-binding properties of two-domain IdeR from Mycobacterium tuberculosis
ChainD
Resolution2.403 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D R27 A28 R29 P39 S42 R60 R27 A28 R29 P39 S42 R60 PDBbind-CN: Kd=4uM
BS02 dna D N2 T7 Q36 S37 P39 T40 R47 R50 N2 T7 Q36 S37 P39 T40 R47 R50 PDBbind-CN: Kd=4uM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0046914 transition metal ion binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:2isz, PDBe:2isz, PDBj:2isz
PDBsum2isz
PubMed17209554
UniProtP9WMH1|IDER_MYCTU Iron-dependent repressor IdeR (Gene Name=ideR)

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