Structure of PDB 2hap Chain D

Receptor sequence
>2hapD (length=75) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
KRNRIPLRCTICRKRKVKCDKLRPHCQQCTKTGVAHLCHYMEQTWAEEAE
KELLKDNELKKLRERVKSLEKTLSK
3D structure
PDB2hap Structure of HAP1-18-DNA implicates direct allosteric effect of protein-DNA interactions on transcriptional activation.
ChainD
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D R57 N58 R59 R70 K71 W100 R2 N3 R4 R15 K16 W45
BS02 dna D R57 R59 R63 K71 V72 K73 R2 R4 R8 K16 V17 K18
BS03 ZN D H80 H91 H25 H36
BS04 ZN D C64 C74 C81 C9 C19 C26
BS05 ZN D C64 C81 C84 C93 C9 C26 C29 C38
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:2hap, PDBe:2hap, PDBj:2hap
PDBsum2hap
PubMed9886287
UniProtP0CS82|HAP1_YEASX Heme-responsive zinc finger transcription factor HAP1 (Gene Name=HAP1)

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