Structure of PDB 2gvc Chain D

Receptor sequence
>2gvcD (length=442) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence]
LPTIRKIAIIGAGPSGLVTAKALLAEKAFDQVTLFERRGSPGGVWNYTST
LSNKLPVPSTNPILTTEPIVGPAALPVYPSPLYRDLQTNTPIELMGYCDQ
SFKPQTLQFPHRHTIQEYQRIYAQPLLPFIKLATDVLDIEKKDGSWVVTY
KGTKAGSPISKDIFDAVSICNGHYEVPYIPNIKGLDEYAKAVPGSVLHSS
LFREPELFVGESVLVVGGASSANDLVRHLTPVAKHPIYQSLLGGGDIQNE
SLQQVPEITKFDPTTREIYLKGGKVLSNIDRVIYCTGYLYSVPFPSLAKL
KSPETKLIDDGSHVHNVYQHIFYIPDPTLAFVGLALHVVPFPTSQAQAAF
LARVWSGRLKLPSKEEQLKWQDELMFSLSGANNMYHSLDYPKDATYINKL
HDWCKQATPVLEEEFPSPYWGEKERSIRENMWSIRAKFFGIE
3D structure
PDB2gvc Mechanism of action of a flavin-containing monooxygenase.
ChainD
Resolution2.22 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.13.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD D G13 G15 P16 S17 E38 R39 R40 G45 V46 W47 L84 T90 N91 T92 D137 V138 N173 G174 Y176 P342 G11 G13 P14 S15 E36 R37 R38 G43 V44 W45 L82 T88 N89 T90 D135 V136 N171 G172 Y174 P340
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0004499 N,N-dimethylaniline monooxygenase activity
GO:0050660 flavin adenine dinucleotide binding
GO:0050661 NADP binding
GO:0071949 FAD binding
Biological Process
GO:1990748 cellular detoxification
Cellular Component
GO:0005789 endoplasmic reticulum membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2gvc, PDBe:2gvc, PDBj:2gvc
PDBsum2gvc
PubMed16777962
UniProtQ9HFE4|FMO1_SCHPO Thiol-specific monooxygenase (Gene Name=fmo1)

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