Structure of PDB 2guo Chain D

Receptor sequence

>2guoD (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]

GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE

3D structure

PDB

2guo Structures of MART-1(26/27-35) Peptide/HLA-A2 Complexes Reveal a Remarkable Disconnect between Antigen Structural Homology and T Cell Recognition

Chain

Resolution

1.9 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	D	Y7 E63 K66 H70 D77 Y84 R97 Y99 Y116 T143 W147 Y159 W167 Y171	Y7 E63 K66 H70 D77 Y84 R97 Y99 Y116 T143 W147 Y159 W167 Y171

External links

PDB	RCSB:2guo, PDBe:2guo, PDBj:2guo
PDBsum	2guo
PubMed	17719062
UniProt	P04439\|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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