Structure of PDB 2fzc Chain D

Receptor sequence
>2fzcD (length=152) Species: 562 (Escherichia coli) [Search protein sequence]
THDNKLQVEAIKRGTVIDHIPAQIGFKLLSLFKLTETDQRITIGLNLPSG
EMGRKDLIKIENTFLSEDQVDQLALYAPQATVNRIDNYEVVGKSRPSLPE
RIDNVLVCPNSNCISHAEPVSSSFAVRKRANDIALKCKYCEKEFSHNVVL
AN
3D structure
PDB2fzc T-state Inhibitors of E. coli Aspartate Transcarbamoylase that Prevent the Allosteric Transition.
ChainD
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.3.2: aspartate carbamoyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN D C109 C114 C138 C141 C108 C113 C137 C140
BS02 CTP D A11 V17 D19 H20 N84 Y89 V91 A10 V16 D18 H19 N83 Y88 V90
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process
GO:0006221 pyrimidine nucleotide biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0009347 aspartate carbamoyltransferase complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:2fzc, PDBe:2fzc, PDBj:2fzc
PDBsum2fzc
PubMed16906764
UniProtP0A7F3|PYRI_ECOLI Aspartate carbamoyltransferase regulatory chain (Gene Name=pyrI)

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