Structure of PDB 2eb5 Chain D

Receptor sequence
>2eb5D (length=259) Species: 562 (Escherichia coli) [Search protein sequence]
MFDKHTHTLIAQRLDQAEKQREQIRAISLDYPEITIEDAYAVQREWVRLK
IAEGRTLKGHKIGLTSKAMQASSQISEPDYGALLDDMFFHDGSDIPTDRF
IVPRIEVELAFVLAKPLRGPNCTLFDVYNATDYVIPALELIDARCHNIKV
FDTISDNAANAGVILGGRPIKPDELDLRWISALMYRNGVIEETGVAAGVL
NHPANGVAWLANKLAPYDVQLEAGQIILGGSFTRPVPARKGDTFHVDYGN
MGSISCRFV
3D structure
PDB2eb5 Structure and Mechanism of HpcG, a Hydratase in the Homoprotocatechuate Degradation Pathway of Escherichia coli
ChainD
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.1.1.77: 2-oxo-3-hexenedioate decarboxylase.
4.2.1.80: 2-oxopent-4-enoate hydratase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG D E106 E108 E139 E106 E108 E139
BS02 OXL D K61 G63 L64 E106 S239 K61 G63 L64 E106 S231
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008684 2-oxopent-4-enoate hydratase activity
GO:0016829 lyase activity
GO:0018817 2-oxo-hept-3-ene-1,7-dioate hydratase activity
GO:0034856 2-hydroxyhexa-2,4-dienoate hydratase activity
GO:0046872 metal ion binding
GO:0047437 4-oxalocrotonate decarboxylase activity
Biological Process
GO:0009056 catabolic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:2eb5, PDBe:2eb5, PDBj:2eb5
PDBsum2eb5
PubMed17559873
UniProtQ46982

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