Structure of PDB 2e89 Chain D

Receptor sequence
>2e89D (length=313) Species: 63363 (Aquifex aeolicus) [Search protein sequence]
MNPESRVIRKVLALQNDEKIFSGERRVLIAFSGGVDSVVLTDVLLKLKNY
FSLKEVALAHFNHMLRESAERDEEFCKEFAKERNMKIFVGKEDVRAFAKE
NRMSLEEAGRFLRYKFLKEILESEGFDCIATAHHLNDLLETSLLFFTRGT
GLDGLIGFLPKEEVIRRPLYYVKRSEIEEYAKFKGLRWVEDETNYEVSIP
RNRIRHRVIPELKRINENLEDTFLKMVKVLRAEREFLEEEAQKLYKEVKK
GNCLDVKKLKEKPLALQRRVIRKFIGEKDYEKVELVRSLLEKGGEVNLGK
GKVLKRKERWLCF
3D structure
PDB2e89 Structural basis of the initial binding of tRNA(Ile) lysidine synthetase TilS with ATP and L-lysine
ChainD
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.4.19: tRNA(Ile)-lysidine synthetase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP D A30 F31 S32 A59 F61 R113 T131 A132 H133 R201 A30 F31 S32 A59 F61 R113 T131 A132 H133 R201
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0016879 ligase activity, forming carbon-nitrogen bonds
GO:0032267 tRNA(Ile)-lysidine synthase activity
Biological Process
GO:0006400 tRNA modification
GO:0008033 tRNA processing
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:2e89, PDBe:2e89, PDBj:2e89
PDBsum2e89
PubMed
UniProtO67728|TILS_AQUAE tRNA(Ile)-lysidine synthase (Gene Name=tilS)

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