Structure of PDB 2ddr Chain D

Receptor sequence
>2ddrD (length=298) Species: 1396 (Bacillus cereus) [Search protein sequence]
DTLKVMTHNVYMLSTNLYPNWGQTERADLIGAADYIKNQDVVILNEVFDN
SASDRLLGNLKKEYPNQTAVLGRSSGSEWDKTLGNYSSSTPEDGGVAIVS
KWPIAEKIQYVFAKGCGPDNLSNKGFVYTKIKKNDRFVHVIGTHLQAEDS
MCGKTSPASVRTNQLKEIQDFIKNKNIPNNEYVLIGGDMNVNKINAENNN
DSEYASMFKTLNASVPSYTGHTATWDATTNSIAKYNFPDSPAEYLDYIIA
SKDHANPSYIENKVLQPKSPQWTVTSWFQKYTYNDYSDHYPVEATISM
3D structure
PDB2ddr Structural Basis of the Sphingomyelin Phosphodiesterase Activity in Neutral Sphingomyelinase from Bacillus cereus.
ChainD
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.4.12: sphingomyelin phosphodiesterase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA D F55 N57 R80 E99 D100 F48 N50 R73 E92 D93
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004620 phospholipase activity
GO:0004767 sphingomyelin phosphodiesterase activity
GO:0008081 phosphoric diester hydrolase activity
GO:0016787 hydrolase activity
Biological Process
GO:0031640 killing of cells of another organism
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2ddr, PDBe:2ddr, PDBj:2ddr
PDBsum2ddr
PubMed16595670
UniProtP11889|PHL2_BACCE Sphingomyelinase C (Gene Name=sph)

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