Structure of PDB 1z0s Chain D

Receptor sequence
>1z0sD (length=249) Species: 2234 (Archaeoglobus fulgidus) [Search protein sequence]
MRAAVVYKTDGHVKRIEEALKRLEVEVELFNQPSEELENFDFIVSVGGDG
TILRILQKLKRCPPIFGINTGRVGLLTHASPENFEVELKKAVEKFEVERF
PRVSCSAMPDVLALNEIAVLSRKPAKMIDVALRVDGVEVDRIRCDGFIVA
TQIGSTGYAFSAGGPVVEPYLECFILIPIAPFRFGWKPYVVSMERKIEVI
AEKAIVVADGQKSVDFDGEITIEKSEFPAVFFKNEKRFRNLFGKVRSIG
3D structure
PDB1z0s Crystal Structures of an NAD Kinase from Archaeoglobus fulgidus in Complex with ATP, NAD, or NADP
ChainD
Resolution1.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E96 C105
Catalytic site (residue number reindexed from 1) E96 C105
Enzyme Commision number 2.7.1.23: NAD(+) kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP D A125 K126 M127 D145 F182 A125 K126 M127 D145 F182
BS02 ATP D R54 E116 G157 Y158 S161 D209 R54 E116 G157 Y158 S161 D209
BS03 POP D G48 G50 T51 R54 R72 G48 G50 T51 R54 R72
Gene Ontology
Molecular Function
GO:0003951 NAD+ kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016773 phosphotransferase activity, alcohol group as acceptor
GO:0046872 metal ion binding
GO:0051287 NAD binding
Biological Process
GO:0006741 NADP biosynthetic process
GO:0016310 phosphorylation
GO:0019674 NAD metabolic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:1z0s, PDBe:1z0s, PDBj:1z0s
PDBsum1z0s
PubMed16242716
UniProtO30297|NADK_ARCFU NAD kinase (Gene Name=nadK)

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