Structure of PDB 1ww4 Chain D

Receptor sequence
>1ww4D (length=160) Species: 64608 (Agrocybe cylindracea) [Search protein sequence]
TTSAVNIYNISAGASVDLAAPVTTGDIVTFFSSALNLSAGAGSPNNTALN
LLSENGAYLLHIAFRLQENVIVFNSRQPNAPWLVEQRVSNVANQFIGSGG
KAMVTVFDHGDKYQVVINEKTVIQYTKQISGTTSSLSYNSTEGTSIFSTV
VEAVTYTGLA
3D structure
PDB1ww4 Structural Basis of a Fungal Galectin from Agrocybe cylindracea for Recognizing Sialoconjugate
ChainD
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.21.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 BGC D R66 E86 R65 E85
BS02 GAL D N46 H62 N75 W83 E86 N45 H61 N74 W82 E85
BS03 SIA D P45 R77 W83 P44 R76 W82
Gene Ontology
Molecular Function
GO:0004518 nuclease activity
GO:0004536 DNA nuclease activity
GO:0030246 carbohydrate binding
GO:0030247 polysaccharide binding
Biological Process
GO:0006259 DNA metabolic process
GO:0006915 apoptotic process
GO:0043065 positive regulation of apoptotic process
Cellular Component
GO:0005575 cellular_component

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Cellular Component
External links
PDB RCSB:1ww4, PDBe:1ww4, PDBj:1ww4
PDBsum1ww4
PubMed16051274
UniProtQ6WY08|ATLE_CYCAE Anti-tumor lectin (Fragment)

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