Structure of PDB 1wsg Chain D

Receptor sequence
>1wsgD (length=155) Species: 562 (Escherichia coli) [Search protein sequence]
MLKQVEIFTDGSCLGNPGPGGYGAILRYRGREKTFSAGYTRTTNNRMALM
AAIVALEALKEHCEVILSTDSQYVRQGITQWIHNWKARGWKTADKKPVKN
VDLWQRLDAALGQHQIKWEWVKGHAGHPENERCNELARAAAMNPTLEDTG
YQVEV
3D structure
PDB1wsg Identification of Single Mn(2+) Binding Sites Required for Activation of the Mutant Proteins of E.coli RNase HI at Glu48 and/or Asp134 by X-ray Crystallography
ChainD
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D10 G11 A48 D70 H124 N134
Catalytic site (residue number reindexed from 1) D10 G11 A48 D70 H124 N134
Enzyme Commision number 3.1.26.4: ribonuclease H.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN D D10 G11 D10 G11
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity
GO:0004523 RNA-DNA hybrid ribonuclease activity
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006401 RNA catabolic process
GO:0043137 DNA replication, removal of RNA primer
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1wsg, PDBe:1wsg, PDBj:1wsg
PDBsum1wsg
PubMed15644213
UniProtP0A7Y4|RNH_ECOLI Ribonuclease HI (Gene Name=rnhA)

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