Structure of PDB 1vlh Chain D

Receptor sequence
>1vlhD (length=158) Species: 2336 (Thermotoga maritima) [Search protein sequence]
MKAVYPGSFDPITLGHVDIIKRALSIFDELVVLVTENPRKKCMFTLEERK
KLIEEVLSDLDGVKVDVHHGLLVDYLKKHGIKVLVRGLRAVTDYEYELQM
ALANKKLYSDLETVFLIASEKFSFISSSLVKEVALYGGDVTEWVPPEVAR
ALNEKLKE
3D structure
PDB1vlh Crystal structure of Phosphopantetheine adenylyltransferase (TM0741) from Thermotoga maritima at 2.20 A resolution
ChainD
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H16 K40 R89 S127
Catalytic site (residue number reindexed from 1) H16 K40 R89 S127
Enzyme Commision number 2.7.7.3: pantetheine-phosphate adenylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PNS D G7 S8 T35 E36 N37 K40 L71 L72 R86 Y96 M100 G7 S8 T35 E36 N37 K40 L71 L72 R86 Y96 M100
BS02 PNS D E132 Y136 E132 Y136
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004595 pantetheine-phosphate adenylyltransferase activity
GO:0005524 ATP binding
GO:0016779 nucleotidyltransferase activity
Biological Process
GO:0009058 biosynthetic process
GO:0015937 coenzyme A biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:1vlh, PDBe:1vlh, PDBj:1vlh
PDBsum1vlh
PubMed
UniProtQ9WZK0|COAD_THEMA Phosphopantetheine adenylyltransferase (Gene Name=coaD)

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