Structure of PDB 1uw5 Chain D

Receptor sequence
>1uw5D (length=268) Species: 9606 (Homo sapiens) [Search protein sequence]
MVLLKEYRVILPVSVDEYQVGQLYSVAEASKNETGGGEGVEVLVNEPYEK
DGEKGQYTHKIYHLQSKVPTFVRMLAPEGALNIHEKAWNAYPYCRTVITN
EYMKEDFLIKIETWHKPDLGTQENVHKLEPEAWKHVEAVYIDIADRSQVL
SKDYKAEEDPAKFKSIKTGRGPLGPNWKQELVNQKDCPYMCAYKLVTVKF
KWWGLQNKVENFIHKQERRLFTNFHRQLFCWLDKWVDLTMDDIRRMEEET
KRQLDEMRQKDPVKGMTA
3D structure
PDB1uw5 Structure-Function Analysis of Human [Corrected] Phosphatidylinositol Transfer Protein Alpha Bound to Phosphatidylinositol.
ChainD
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PIE D T58 K60 Y62 E85 T96 I111 K194 E217 L220 F224 T58 K60 Y62 E85 T96 I111 K194 E217 L220 F224
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005548 phospholipid transporter activity
GO:0008289 lipid binding
GO:0008525 phosphatidylcholine transporter activity
GO:0008526 phosphatidylinositol transfer activity
GO:0031210 phosphatidylcholine binding
GO:0035091 phosphatidylinositol binding
GO:0120019 phosphatidylcholine transfer activity
GO:1901611 phosphatidylglycerol binding
Biological Process
GO:0006629 lipid metabolic process
GO:0006869 lipid transport
GO:0007409 axonogenesis
GO:0007601 visual perception
GO:0015914 phospholipid transport
GO:0120009 intermembrane lipid transfer
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0070062 extracellular exosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1uw5, PDBe:1uw5, PDBj:1uw5
PDBsum1uw5
PubMed14962392
UniProtQ00169|PIPNA_HUMAN Phosphatidylinositol transfer protein alpha isoform (Gene Name=PITPNA)

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