Structure of PDB 1s20 Chain D

Receptor sequence
>1s20D (length=334) Species: 562 (Escherichia coli) [Search protein sequence]
MKVTFEQLKAAFNRVLISRGVDSETADACAEMFARTTESGVYSHGVNRFP
RFIQQLENGDIIPDAQPKRITSLGAIEQWDAQRSIGNLTAKKMMDRAIEL
AADHGIGLVALRNANHWMRGGSYGWQAAEKGYIGICWTNSIAVMPPWGAK
ECRIGTNPLIVAIPSTPITMVDMSMSMFSYGMLEVNRLAGRQLPVDGGFD
DEGNLTKEPGVIEKNRRILPMGYWKGSGMSIVLDMIATLLSDGASVAEVT
QDNSDEYGISQIFIAIEVDKLIDGPTRDAKLQRIMDYVTSAERADENQAI
RLPGHEFTTLLAENRRNGITVDDSVWAKIQALLE
3D structure
PDB1s20 A Novel NAD-binding Protein Revealed by the Crystal Structure of 2,3-Diketo-L-gulonate Reductase (YiaK).
ChainD
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H44
Catalytic site (residue number reindexed from 1) H44
Enzyme Commision number 1.1.1.130: 3-dehydro-L-gulonate 2-dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD D H44 H116 T156 P158 D172 M173 S174 E306 H44 H116 T156 P158 D172 M173 S174 E306
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0047559 3-dehydro-L-gulonate 2-dehydrogenase activity
GO:0070403 NAD+ binding
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:1s20, PDBe:1s20, PDBj:1s20
PDBsum1s20
PubMed14718529
UniProtP37672|DLGD_ECOLI 2,3-diketo-L-gulonate reductase (Gene Name=dlgD)

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