Structure of PDB 1rjw Chain D

Receptor sequence
>1rjwD (length=339) Species: 1422 (Geobacillus stearothermophilus) [Search protein sequence]
MKAAVVEQFKEPLKIKEVEKPTISYGEVLVRIKACGVCHTDLHAAHGDWP
VKPKLPLIPGHEGVGIVEEVGPGVTHLKVGDRVGIPWLYSACGHCDYCLS
GQETLCEHQKNAGYSVDGGYAEYCRAAADYVVKIPDNLSFEEAAPIFCAG
VTTYKALKVTGAKPGEWVAIYGIGGLGHVAVQYAKAMGLNVVAVDIGDEK
LELAKELGADLVVNPLKEDAAKFMKEKVGGVHAAVVTAVSKPAFQSAYNS
IRRGGACVLVGLPPEEMPIPIFDTVLNGIKIIGSIVGTRKDLQEALQFAA
EGKVKTIIEVQPLEKINEVFDRMLKGQINGRVVLTLEDK
3D structure
PDB1rjw Crystal Structure and Amide H/D Exchange of Binary Complexes of Alcohol Dehydrogenase from Bacillus stearothermophilus: Insight into Thermostability and Cofactor Binding
ChainD
Resolution2.35 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) C38 H39 T40 H43 H61 E62 C92 C95 C98 C106 K110 C148 T152 R331
Catalytic site (residue number reindexed from 1) C38 H39 T40 H43 H61 E62 C92 C95 C98 C106 K110 C148 T152 R331
Enzyme Commision number 1.1.1.1: alcohol dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN D C92 C95 C98 C106 C92 C95 C98 C106
BS02 ZN D C38 H61 C148 C38 H61 C148
BS03 ETF D T40 H61 W87 I285 T40 H61 W87 I285
BS04 ETF D D219 A220 S246 D219 A220 S246
BS05 ETF D H43 L262 P264 H43 L262 P264
Gene Ontology
Molecular Function
GO:0004022 alcohol dehydrogenase (NAD+) activity
GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:1rjw, PDBe:1rjw, PDBj:1rjw
PDBsum1rjw
PubMed15122892
UniProtP42328|ADH3_GEOSE Alcohol dehydrogenase

[Back to BioLiP]