Structure of PDB 1r5v Chain D

Receptor sequence
>1r5vD (length=185) Species: 10090 (Mus musculus) [Search protein sequence]
APWFLEYSKSECHFYNGTQRVRLLVRYFYNLEENLRFDSDVGEFRAVTEL
GRPDAENWNSQPEFLEQKRAEVDTVCRHNYEIFDNFLVPRRVEPTVTVYP
TKTQPLEHHNLLVCSVSDFYPGNIEVRWFRNGKEEKTGIVSTGLVRNGDW
TFQTLVMLETVPQSGEVYTCQVEHPSLTDPVTVEW
3D structure
PDB1r5v Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation.
ChainD
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D E36 S40 D84 N87 W88 E101 H108 N109 I112 F113 E6 S10 D54 N57 W58 E71 H78 N79 I82 F83
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1r5v, PDBe:1r5v, PDBj:1r5v
PDBsum1r5v
PubMed14690592
UniProtP18468|HB2I_MOUSE H-2 class II histocompatibility antigen, I-A beta chain (Gene Name=H2-Eb1)

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