Structure of PDB 1r0l Chain D

Receptor sequence
>1r0lD (length=378) Species: 542 (Zymomonas mobilis) [Search protein sequence]
QPRTVTVLGATGSIGHSTLDLIERNLDRYQVIALTANRNVKDLADAAKRT
NAKRAVIADPSLYNDLKEALAGSSVEAAAGADALVEAAMMGADWTMAAII
GCAGLKATLAAIRKGKTVALANKESLVSAGGLMIDAVREHGTTLLPVDSE
HNAIFQCFPHHNRDYVRRIIITASGGPFRTTSLAEMATVTPERAVQHAKI
SIDSATMMNKGLELIEAFHLFQIPLEKFEILVHPQSVIHSMVEYLDGSIL
AQIGSPDMRTPIGHTLAWPKRMETPAESLDFTKLRQMDFEAPDYERFPAL
TLAMESIKSGGARPAVMNAANEIAVAAFLDKKIGFLDIAKIVEKTLDHYT
PATPSSLEDVFAIDNEARIQAAALMESL
3D structure
PDB1r0l Crystal structure of 1-deoxy-d-xylulose-5-phosphate reductoisomerase from Zymomonas mobilis at 1.9-A resolution.
ChainD
Resolution2.7 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.1.1.267: 1-deoxy-D-xylulose-5-phosphate reductoisomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NDP D G11 T13 G14 A38 N39 R40 N41 A60 I102 A105 G9 T11 G12 A36 N37 R38 N39 A58 I100 A103
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0030145 manganese ion binding
GO:0030604 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GO:0046872 metal ion binding
GO:0070402 NADPH binding
Biological Process
GO:0008299 isoprenoid biosynthetic process
GO:0019288 isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
GO:0051484 isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1r0l, PDBe:1r0l, PDBj:1r0l
PDBsum1r0l
PubMed15063313
UniProtQ9X5F2|DXR_ZYMMO 1-deoxy-D-xylulose 5-phosphate reductoisomerase (Gene Name=dxr)

[Back to BioLiP]