Structure of PDB 1qp9 Chain D

Receptor sequence
>1qp9D (length=75) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
RKRNRIPLGCTICRKRKVKCDKLRPHCQQCTKTGVAHLCHYMEQTWAEEA
EKELLKDNELKKLRERVKSLEKTLS
3D structure
PDB1qp9 Structure of HAP1-PC7 bound to DNA: implications for DNA recognition and allosteric effects of DNA-binding on transcriptional activation.
ChainD
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna D R57 N58 R59 K71 R3 N4 R5 K17 PDBbind-CN: Kd=37.8nM
BS02 dna D K56 R57 R59 P61 K71 V72 K73 K2 R3 R5 P7 K17 V18 K19 PDBbind-CN: Kd=37.8nM
BS03 ZN D H80 H91 H26 H37
BS04 ZN D C64 C67 C74 C81 C10 C13 C20 C27
BS05 ZN D C64 C81 C84 C93 C10 C27 C30 C39
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:1qp9, PDBe:1qp9, PDBj:1qp9
PDBsum1qp9
PubMed11024163
UniProtP0CS82|HAP1_YEASX Heme-responsive zinc finger transcription factor HAP1 (Gene Name=HAP1)

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