Structure of PDB 1pzk Chain D

Receptor sequence
>1pzkD (length=103) Species: 666 (Vibrio cholerae) [Search protein sequence]
TPQNITDLCAEYHNTQIHTLNDKIFSYTESLAGKREMAIITFKNGATFQV
EVPGSQHIDSQKKAIERMKDTLRIAYLTEAKVEKLCVWNNKTPHAIAAIS
MAN
3D structure
PDB1pzk 3,5-Substituted phenyl galactosides as leads in designing effective cholera toxin antagonists; synthesis and crystallographic studies
ChainD
Resolution1.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 J12 D Y12 E51 Q56 H57 Q61 W88 N90 K91 Y12 E51 Q56 H57 Q61 W88 N90 K91 MOAD: ic50=0.2mM
BS02 J12 D K34 R35 K34 R35 MOAD: ic50=0.2mM
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:1pzk, PDBe:1pzk, PDBj:1pzk
PDBsum1pzk
PubMed14980603
UniProtQ57193

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