Structure of PDB 1pn4 Chain D

Receptor sequence
>1pn4D (length=273) Species: 5482 (Candida tropicalis) [Search protein sequence]
DPVWRFDDRDVILYNIALGATTKQLKYVYENDSDFQVIPTFGHLITFNSG
KSQNSFAKLLRNFNPMLLLHGEHYLKVHSWPPPTEGEIKTTFEPIATTPK
GTNVVIVHGSKSVDNKSGELIYSNEATYFIRNCQADNKVYADRPAFATNQ
FLAPKRAPDYQVDVPVSEDLAALYRLSGDRNPLQIDPNFAKGAKFPKPIL
HGMCTYGLSAKALIDKFGMFNEIKARFTGIVFPGETLRVLAWKESDDTIV
FQTHVVDRGTIAINNAAIKLVGD
3D structure
PDB1pn4 A Two-domain Structure of One Subunit Explains Unique Features of Eukaryotic Hydratase 2.
ChainD
Resolution2.35 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D182 Q187 I202 G205
Catalytic site (residue number reindexed from 1) D179 Q184 I199 G202
Enzyme Commision number 1.1.1.n12: (3R)-hydroxyacyl-CoA dehydrogenase.
4.2.1.119: enoyl-CoA hydratase 2.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HDC D L72 H73 G74 K103 V108 F132 D182 N184 Q187 G205 R229 F230 T231 G232 I233 L69 H70 G71 K100 V105 F129 D179 N181 Q184 G202 R226 F227 T228 G229 I230
External links
PDB RCSB:1pn4, PDBe:1pn4, PDBj:1pn4
PDBsum1pn4
PubMed15051722
UniProtP22414|FOX2_CANTR Peroxisomal hydratase-dehydrogenase-epimerase

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