Structure of PDB 1ofq Chain D

Receptor sequence
>1ofqD (length=346) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
VRILGYDPLASPALLQVQIPATPTSLETAKRGRREAIDIITGKDDRVLVI
VGPCSIHDLEAAQEYALRLKKLSDELKGDLSIIMRAYLEPRTTVGWKGLI
NDPDVNNTFNINKGLQSARQLFVNLTNIGLPIGSEMLDTISPQYLADLVS
FGAIGARTTESQLHRELASGLSFPVGFKNGTDGTLNVAVDACQAAAHSHH
FMGVTKHGVAAITTTKGNEHCFVILRGGKKGTNYDAKSVAEAKAQLPAGS
NGLMIDYSHGNSNKDFRNQPKVNDVVCEQIANGENAITGVMIESNINEGN
QGIPAEGKAGLKYGVSITDACIGWETTEDVLRKLAAAVRQRREVNK
3D structure
PDB1ofq Substrate and Metal Complexes of 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase from Saccharomyces Cerevisiae Provide New Insights Into the Catalytic Mechanism
ChainD
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.54: 3-deoxy-7-phosphoheptulonate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN D C4076 H4282 E4316 D4342 C54 H259 E293 D319
Gene Ontology
Molecular Function
GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity
GO:0016740 transferase activity
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009058 biosynthetic process
GO:0009073 aromatic amino acid family biosynthetic process
GO:0009423 chorismate biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:1ofq, PDBe:1ofq, PDBj:1ofq
PDBsum1ofq
PubMed15019786
UniProtP32449|AROG_YEAST Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited (Gene Name=ARO4)

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